Category:Electronic componentsTonsils and adenoids are two of the most common sites of infection in childhood. Following tonsillectomy or adenoidectomy, the majority of patients who had previously received antibiotics have recurrent adenotonsillar infection within 6-12 months, and are at high risk of a late period of nasal colonization with penicillin-resistant streptococci (P.R.S.). For this study, 30 children, ages 8 months through 5 years, scheduled for elective tonsillectomy or adenoidectomy, will be studied before the procedure, during the operation, and for up to 6 weeks postoperatively. Following surgery, all patients will receive either 3 days or 1 week of antibiotic therapy with ampicillin and clindamycin, and randomly assigned to one of the two study groups: Group I will be given either penicillin and clindamycin or saline drops, to be applied 4 times a day for 1 week following surgery; Group II will receive penicillin and saline drops to be applied 4 times a day for 3 days following surgery. Nasal cultures will be obtained before surgery and before each postoperative antibiotic change, and again at 5 and 6 weeks postoperatively. Of the 120 cultures obtained from patients enrolled in the study, a total of 50 will be strep positive, of which 39 will be P.R.S. These patients will be treated with either penicillin or clindamycin for 1 week. If there is a recurrence of infection, the patient will be placed in an intensified maintenance antibiotic course (possibly including aminoglycosides) for up to 8 weeks. Patients who fail to respond to antibiotic treatment will be treated with a combination of clindamycin and erythromycin, and if they continue to have disease, will be placed on a penicillin-based maintenance regimen for an additional 4 weeks. The total duration of treatment for the first infection will be 3 weeks, and for any subsequent infection 4 weeks. The data obtained will be evaluated with regard to the infection rate, the types of resistant organisms isolated, and the efficacy of each of the antibiotic treatments.[Catecholamines in peripheral blood. A new method of analysis].
A new method for the determination of the concentration of catecholamines in small volumes of peripheral blood is presented. Plasma catecholamines are separated from red blood cells by means of a small-pore agarose gel chrom be359ba680
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